- exhibits a stimulating effect;
- enhances regeneration processes in the body;
- increases tissue resistance to external influences;
- resists stress and mental strain;
- actively counteracts the development of alcohol and drug addiction;
- balances metabolism, reducing appetite and promoting weight loss;
- reduces the threshold of pain sensitivity, especially when exposed to temperature;
- regulates the production of growth hormone, hemoglobin, nitrogen concentration in the body;
- improves the condition of common sclerosis.
- for depression, sleep disorders;
- migraine;
- as a component in the treatment of alcoholism and drug addiction;
- with physical stress;
- its deficiency in the body;
- overweight;
- functional disorders in the food and urinary system;
- detoxification;
- injuries with violation of tissue integrity.
- severe dysfunction of the liver, kidneys, heart;
- pregnancy and breastfeeding;
- if the patient is under 18;
- diabetes mellitus, hepatitis, metabolic disorders;
- individual intolerance.
- the amino acid is always taken together with leucine and isoleucine (the dosage is calculated by the doctor);
- valine is never consumed simultaneously with tryptophan and tyrosine, as it reduces their penetration into brain cells;
- the amino acid is perfectly absorbed during meals - with cereals,
Valine is an aliphatic (branched) amino acid, which is part of 70% of proteins, but is not synthesized by the body. Acts as a matrix for the synthesis of pantothenic acid (vitamin B5) and penicillin (valinomycin). The importance of this amino acid is difficult to overestimate: the body is not able to fully function without the L (L) and D (D) isomers of valine, since they supply the energy used in muscle tissue and are responsible for the ability of the body to move in space.
Characteristic
Valine was first obtained in the laboratory in 1901 by the German chemist Emil Fischer from the hydrolysis of casein. named after valerian because it is involved in stimulating the body's activity, thereby maintaining its structural integrity.
According to its characteristics, valine is similar to isoleucine. This amino acid is hydrophobic, therefore almost inert to chemical and biochemical processes in the body, but it determines the three-dimensionality of proteins and can absorb other amino acids.
Valine is also called a glucogen amino acid for the ability of its isomers to be transformed in the liver into glucose - the most accessible source of energy for muscles. In parallel, vitamin B3 is synthesized from valine isomers.
Pharmacological properties
The very name of the amino acid suggests that its main property is its effect on the central nervous system with the regulation of the processes of inhibition and excitation.
In addition, she:
Daily requirement
A person needs about 2-4 g of valine per day. The exact dosage is calculated using the formula: 10 mg of amino acid per 1 kg of body weight. If it is necessary to increase the dose, not 10, but 26 mg of the biological substance is taken as the starting point.
Remember that when taking valine preparations, any dose calculations are made by the doctor, since the compound has serious contraindications for use and can bring not only benefit, but also harm. In case of insufficiency of liver or kidney function, hemolytic anemia, diabetes, pathology of the gastrointestinal tract, the use of the amino acid is limited.
Food sources
Since valine is an essential amino acid, its concentration in the body depends solely on its intake through foods. The top amino acid content in food products in correlation with nutritional value is presented in the table.
| 100 g of product | Amino acid in mg |
| Cheese: Parmesan, Edam, goat, processed, Swiss | 2500 |
| Cottage cheese, eggs, milk, yogurt | 2400 |
| , legumes, nuts, corn | 2000 |
| Sea kale, seafood | 1950 |
| Meat (except pork) | 1900 |
| Poultry, fish (except tuna), pork (tenderloin) | 1600 |
| Pumpkin seeds | 1580 |
| 1500 | |
| Mushrooms, wild rice, buckwheat, | 400 |
| Whole grains | 300 |
B5 is most easily absorbed from nuts and eggs.
Indications
Contraindications
Valine is always prescribed after a clinical and laboratory examination and is contraindicated in the following cases:
Side effects
In case of overdose, symptoms of intoxication are observed: nausea, fever, vomiting, rapid heartbeat, delirium.
Valine deficiency is manifested by weakness and increased fatigue, impaired concentration.
Interaction with other substances
When taking a substance in combination with other drugs, it is necessary to take into account its features:
As one of the 20 essential dietary amino acids, valine is an amino acid, part of almost all known proteins. It is an essential amino acid, which means it cannot be synthesized by the human body and its only source will be from the outside, along with food or nutritional supplements.
Valine is a very important component for tissue growth and synthesis. Valine has properties maintaining the proper level of serotonin and, together with leucine and isoleucine, serves as a significant source of energy in the body. Being a branched compound, valine can serve either role. Animal experiments have shown that this amino acid increases muscle coordination. Reduces sensitivity to changes in ambient temperature and increases the pain threshold. This makes the amino acid, named after the valerian plant, a good help for those who play sports, bodybuilding, and want to lead a healthy and fulfilling lifestyle.
Valine and its properties affecting human health
Valine supports normal nitrogen metabolism in the body and ensures all processes associated with it. Consumption valine from products and in preparations allows for both prevention and treatment of a whole range of diseases and complications associated with amino acid deficiency. These include a number of severe addictions, such as drug addiction, depression, and multiple sclerosis. Long-term courses of taking valine allow you to soften the course and achieve a gradual resolution of addictions.
Valine and products that contain it
Common, everyday foods that contain valine include mushrooms, meat, dairy products, soy and peanuts. Its highest concentration will be in soybeans, peas, beans and beef liver. In addition, entire amino acid complexes of sports nutrition have been developed that are capable of providing the body with all 20 essential amino acids involved in the formation of proteins and various processes in the body, including essential acids, which include valine. As always, maintaining a healthy, balanced diet, including supplements as needed, is the cornerstone of human health and is a top priority for each of us.
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Graduated from: Belarusian State Pedagogical University named after M. Tank. Specialty: social work, pedagogy. Courses on health-improving fitness and bodybuilding at the Belarusian State University of Physical Culture, at the department of health-improving physical culture. Master of Masters in arm wrestling, 1st adult category in hand-to-hand combat. Prize-winner of the Cup of the Republic of Belarus in hand-to-hand combat. Prize-winner of the Republican Dynamyade in hand-to-hand combat.
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Date of: 2014-09-12 Views: 16 339 Amino acids are the main material for protein cells that form hormones, tissues, and ligaments. These can be nonessential or essential amino acids. Essential amino acids (branched amino acids) are very important for the body, especially during physical activity. Let's look at the essential amino acid - valine. Let's try to understand its effectiveness and methods of application. Valine is a branched chain amino acid. It is not synthesized in the body and must be supplied with food. Part of many proteins. There is a lot of it in albumin and connective tissue proteins. Pantothenic acid (vitamin B5) is synthesized from valine. Vitamin B5 is an excellent substance for combating stress and physical fatigue.
Functions of valine
1. Restores muscle tissue after heavy physical activity.
Accelerates protein synthesis, which cannot but affect and. Without branched amino acids, in particular valine, metabolism slows down. Also, the regeneration process becomes impossible.
2. Participates in the formation of energy.
Valine is used by muscles to release energy, along with isoleucine and leucine, as it has developed side chains in its structure. Improves coordination of muscle contractions, thereby increasing dexterity and accuracy of movements.
3. Participates in maintaining nitrogen balance.
In bodybuilding, to gain muscle mass, athletes try to change the nitrogen balance in a positive direction. Therefore, containing valine, it is taken together with.
4. Participates in maintaining serotonin levels and the absorption of other proteins.
Due to this function, cases of valine being used in medicine are not uncommon. It is used in the treatment against depressive conditions. If the body is deficient in valine, it leads to the destruction of contractile proteins. Even a slight lack of valine can impair the absorption of other proteins. Valine is found in the following foods:
- Beef,
- Chicken fillet,
- Salmon,
- Cow's milk,
- Chicken eggs,
- Legumes,
When and to whom should it be used?
The ideal time to take supplements containing valine is during the period of mass building. This will strengthen your muscles and reduce cortisol levels. Therefore, if you decide to gain a few kilograms of muscle mass, then valine will be a good assistant in this matter. Just because you don't go to the gym doesn't mean your body doesn't need valine. Valine improves protein metabolism, which means that your performance will increase and the impact of stress will be minimal. As you can see, valine is always needed, be it hard training or hard work.Dosages and side effects
For a person who is not involved in sports, the daily dose of valine is 2-4 g. For people who engage in strength sports, this norm is higher. It is best taken together with leucine and isoleucine. This is possible thanks to the BCAA supplement. A good and working dosage is up to 12 g, and you need to use amino acids before and after strength or cardio training. In order to speed up the recovery process after training, it is recommended to take valine together with. It is unrealistic to bring the body to an excess of valine. Especially if you train hard and lead an active lifestyle. Valine has no contraindications. Personal fitness training from the author of this article:- preparation of training programs and nutrition online,
- weight loss and adjustment,
- gaining muscle mass,
- Exercise therapy for various diseases (including the back),
- rehabilitation after injuries,
In these tables, the average daily requirement for valine is assumed to be 3500 mg (3.5 grams). This is an average figure for the average person. For athletes, the norm of this essential amino acid can reach 6-7 grams per day. The “Percentage of daily requirement” column shows what percentage of 100 grams of product satisfies a person’s daily need for a given amino acid.
FOODS HIGH IN THE AMINO ACID VALINE:
| The product's name | Valine content per 100g | Percentage of daily requirement |
| Egg powder | 2550 mg | 73% |
| Parmesan cheese | 2454 mg | 70% |
| Red granular caviar | 2140 mg | 61% |
| Soybean (grain) | 1737 mg | 50% |
| Cheese "Poshekhonsky" 45% | 1270 mg | 36% |
| Lentils (grain) | 1270 mg | 36% |
| Cheese "Swiss" 50% | 1250 mg | 36% |
| Peanut | 1247 mg | 36% |
| Pink salmon | 1230 mg | 35% |
| Pistachios | 1230 mg | 35% |
| Powdered milk 25% | 1207 mg | 34% |
| Cheese cheese (from cow's milk) | 1200 mg | 34% |
| Cheddar cheese 50% | 1150 mg | 33% |
| Beans (grain) | 1120 mg | 32% |
| Sea bass | 1100 mg | 31% |
| Cashew | 1094 mg | 31% |
| Cheese "Roquefort" 50% | 1080 mg | 31% |
| Sunflower seeds (seeds) | 1071 mg | 31% |
| Chees Feta" | 1065 mg | 30% |
| Meat (beef) | 1030 mg | 29% |
| Peas (shelled) | 1010 mg | 29% |
| Lean herring | 1000 mg | 29% |
| Mackerel | 1000 mg | 29% |
| Low-fat cottage cheese | 990 mg | 28% |
| Zander | 980 mg | 28% |
| Pike | 980 mg | 28% |
| Horse mackerel | 950 mg | 27% |
| Chicken egg yolk | 940 mg | 27% |
| Almond | 940 mg | 27% |
| Meat (turkey) | 930 mg | 27% |
| Chum salmon | 900 mg | 26% |
| Pollock | 900 mg | 26% |
| Cod | 900 mg | 26% |
| Hazelnut | 900 mg | 26% |
| Sesame | 886 mg | 25% |
| Meat (chicken) | 880 mg | 25% |
| Quail egg | 880 mg | 25% |
| Meat (broiler chickens) | 870 mg | 25% |
| Cottage cheese 18% (fat) | 838 mg | 24% |
| Meat (pork meat) | 830 mg | 24% |
| Meat (lamb) | 820 mg | 23% |
Article added: 2017-10-10
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Valin(2-amino-3-methylbutanoic acid L-Valine) is an essential aliphatic amino acid that has a stimulating effect. This is one of the 20 proteinogenic amino acids. It is present in the body as part of proteins and in free form. It got its name in honor of the valerian plant.
For the first time, during a study in 1901, the German chemist G. E. Fischer isolated the aminoisovaleric acid valine from casein.
Valine is a starting substance in the biosynthesis of Vitamin B5 and penicillin. Valine is a branched amino acid, which means it can be used by muscles as a powerful source of energy.
The human body is not capable of producing this amino acid itself, so it must be supplied to it through food and special dietary supplements (dietary supplements). In addition, you need to know how much the body’s daily need for valine is.
The body's daily need for valine
The body's daily need for valine for an ordinary person is 3-4 grams. Depending on age, lifestyle, and health status, this need for valine can range from 1.8 to 5 and in some cases up to 7 g per day. The best effect is achieved when using valine together with and. At the same time, it combines with all amino acids of the protein group.
But we should not forget that a deficiency or excess of this essential amino acid has unpleasant consequences that lead to damage to health.
Consequences of a lack of valine in the body
With a lack of valine in the body, the immune system is weakened, memory deteriorates, sleep is disturbed, and this also affects the decrease in serotonin levels, which provokes mental disorders and despondency. With frequent tension in the muscles of the body, bodybuilding, a lack of valine leads to the destruction of part of the contractile proteins. Deficiency of this essential amino acid causes frequent skin inflammatory diseases, including dermatitis. Even a slight decrease in the amount of valine needed by the body affects the absorption of other amino acids. Children are more vulnerable to a lack of this amino acid, especially those who adhere to a diet in the final stages of food allergies. Their body requires proper nutrition, as little stress and manifestations of depression as possible. This also applies to people on high protein diets. The fact is that valine is involved in the removal of protein metabolic products and in the transport of nitrogen obtained with proteins from the liver to other tissues.
An excess of this proteinogenic amino acid can also have adverse consequences.
Consequences of excess valine in the body
With an excess of valine in the body, fluctuations or deterioration in the passage of nerve impulses occur, this can manifest itself as chills throughout the body, numbness and tingling in the extremities, even hallucinations. Problems with the gastrointestinal tract, blood thickening, and interference with the liver and kidneys may occur. Every person should focus their attention on this point so that you can be completely healthy people and receive only the benefits of taking valine, without negative effects on the body.
Beneficial properties of valine
Valine, like other amino acids, is very important for the life of the body. As mentioned earlier, valine is a powerful source of energy for muscles, it is involved in their development and recovery, which is why it is so often used in bodybuilding. It supports normal nitrogen metabolism in the body. Also, this amino acid promotes the proper functioning of the immune system, tissue regeneration after illnesses, injuries, and has a positive effect on the central nervous system and autonomic nervous system.
Valine prevents the level of serotonin from decreasing, one of the main neurotransmitters that improves mood and adds shine to the eyes. Responsible for many hormonal processes, increases the production of growth hormone, thyroid and adrenal glands. Reduces the sensitivity of the living body to pain, improves adaptation to heat and cold. And in the fight against obesity, this amino acid helps suppress cravings.
Valine is considered an important element in the treatment of bad habits such as alcoholism and smoking. Thanks to him, these weaknesses gradually disappear from a person’s life.
Despite its beneficial properties, valine in the form of dietary supplements also has its contraindications and harms.
Contraindications and harm of valine
Valine supplementation should be done under medical supervision. Independent actions in this direction can end in a sad outcome. It is contraindicated for people with severe liver, kidney and heart failure, children under adulthood, pregnant women, as well as during lactation, hepatitis, diabetes, amino acid metabolism disorders, individual intolerance.
Valine may cause harm due to symptoms such as nausea (vomiting), rapid heartbeat, hallucinations, and chills.
In order not to expose our body to danger, to be more beautiful, calmer and more resistant to stressful situations, you should know which foods contain valine.
Foods rich in valine
We can obtain valine from food products of plant and animal origin. Food products that contain the greatest amount of valine include chicken eggs and fillets, cheeses, cow's milk, beef, salmon, and squid. Valine is also found in unmilled rice, corn flour, walnuts, pistachios, peas, red beans, pumpkin seeds and seaweed.
You also need to know how the food preparation process affects the content of amino acids, including valine.
Effect of food preparation process on valine content
The content of valine changes during food preparation, as is the case with other amino acids. Thus, there is more of this amino acid in boiled or stewed meat, chicken and fish than in raw, canned or fried meat. As for chicken eggs, there is more amino acid valine in fried form than in boiled and raw eggs.
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